Loss Of Appetite But Not Losing Weight
Having a healthy appetite is an essential part of life – it increases our desire to eat and allows us to get the right amount of nutrients we need to stay healthy.
So, how does our appetite work? When we’re hungry, the body recognises our need for food and sends a signal – like a rumbling stomach – to the brain to eat. Hormones play a key role in regulating your body’s appetite. Ghrelin, the ‘hunger hormone’, stimulates your appetite, and leptin tells your brain when you’ve eaten enough.

‘Many factors can affect the regulation of these hormones and can interfere with our appetite drive, ’ explains Dr Rhianna McClymont, Lead GP at . Most of us experience loss of appetite at one point or another – whether it’s because of environmental factors, medication or psychological or physical conditions.
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In most cases, a decreased appetite is only short term, but if it’s longer lasting you may need treatment for an underlying problem. Here are some of the key causes:
‘Viral and bacterial infections – including flu-like illnesses, tummy bugs and urine infections – are a common reason for appetite loss, ’ says Dr McClymont.
‘When you’re unwell, the body releases chemicals called cytokines, which regulate appetite as part of an inflammatory and immune response that act on neurons in the brain. This suppresses our appetite drive, making us less keen to eat.’
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People with poorly controlled diabetes may lose their appetite due to a condition called gastroparesis, where food moves too slowly through the digestive tract due to damaged nerves.
‘Conditions that affect the gut, such as inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS), can affect our appetite through symptoms that make us less inclined to eat – including abdominal pain, bloating, diarrhoea and gut spasms, ’ explains Dr McClymont.
As we age, our appetite changes. It’s estimated that up to 30% of older people experience a reduction in appetite and eat less food, leading to weight loss and nutritional deficiencies. One study found that older people have higher levels of the hormone peptide YY, which makes them feel full.
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You can also experience a reduced appetite as a result of illnesses like Alzheimer’s and Parkinson’s disease or other conditions, including dental and swallowing problems. Lack of exercise, feeling lonely or socially isolated or an inability to prepare meals can also cause a reduced appetite.
Mental health conditions can have a significant impact on your appetite. People experiencing depression often lose interest in food, and our appetite tends to decrease when we’re feeling anxious or stressed or as a consequence of life events like a relationship break-up or the death of a loved one.
‘During stressful events, your brain releases the “fight-or-flight” hormone, adrenaline, which slows down your digestive system, ’ says Dr McClymont. ‘Depression triggers the production of corticotropin-releasing hormone, which also curbs your appetite.’
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Cancer treatments can also cause appetite loss, with around 60% of people diagnosed with cancer experience a loss of appetite. Treatments such as chemotherapy and immunotherapy can cause taste changes and symptoms such as nausea, which is a common side-effect of chemotherapy, can aggravate this further.
‘If you feel one of your medications is causing a change to your appetite, it’s always best to raise this with a doctor. There may be a suitable alternative you can try, ’ advises Dr McClymont.

If you have an underactive thyroid, also known as hypothyroidism, your thyroid gland is not producing enough hormones. This causes many of the body’s functions to slow down, which can result in a loss of appetite. Other symptoms include weight gain, tiredness and depression.
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If a doctor thinks you have an underactive thyroid, they can check the level of thyroid hormones in your body by doing a blood test.
‘Anorexia nervosa is an eating disorder and serious mental health condition characterised by a desire to keep your body weight as low as possible by restricting food intake, over-exercising or both, ’ says Dr McClymont. This condition can also lead to a reduction in appetite.
‘People who suffer from this often have a distorted and negative body image. It requires specialist medical treatment and can be life-threatening in severe cases.’
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Drinking too much alcohol has numerous physical signs, including having a sore or upset stomach, a yellow skin tone and feeling numbness and tingling in your feet and hands. It can also have a big impact on appetite – and you may lose all interest in food as your focus shifts to alcohol.
Although losing your appetite and skipping meals has many different causes, it may also be a direct result of other symptoms, including:
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Covid-19 affects our appetite in the same way as other viruses – but one of its main symptoms, the loss of smell or taste, can also affect our appetite. One study found that 87% of respondents who experienced a loss of smell or taste from Covid-19 experienced a reduced enjoyment of food.
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‘Pregnancy is a common cause of appetite loss, primarily due to nausea, ’ explains Dr McClymont. ‘The term “morning sickness” can occur any time of day and is particularly common in the first trimester.
‘Hyperemesis gravidarum is an extreme form of pregnancy nausea and vomiting, which can lead to dehydration and weight loss. If this is affecting you, it’s important to discuss it with a doctor or midwife because it generally needs treatment with anti-sickness medications and may require hospital admission for fluid rehydration.’
If you’re experiencing fatigue as a result of another condition, it may make you feel less inclined to cook or eat food. ‘Loss of appetite and tiredness are symptoms of other conditions. Often, a loss of appetite will naturally lower your energy reserves, leading to tiredness, ’ says Dr McClymont.
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Appetite loss can have a broad range of causes, but it’s important to speak to a doctor if you notice any other symptoms alongside a loss of appetite, including:
‘If you experience appetite loss that’s persistent and doesn’t seem to be related to a simple explanation, such as a cold or flu virus, speak to a doctor, ’ says Dr McClymont.
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If you’re worried about your appetite loss or think it might be down to an underlying condition, book an appointment to speak to a doctor.
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General health and seasonal – Mar 7, 2023A guide to managing hay fever in children Hay fever season coincides with the time of year when children love being outside. Here are a doctor's tips for managing your child’s hay fever symptoms. Read moreAre you among the many people who feel frustrated with disappointing weight loss results despite regular exercise? If so, you are not alone. Exercise is crucial for maintaining good health and can be a powerful way to lose weight. However, many misconceptions about exercise and weight loss may be holding you back from seeing the desired results. And it should not be the reason to give up as exercising has many important health benefits, including- reducing the risk of chronic disease, improving mental health, and increasing overall well-being. According to WHO, adults should aim for at least 150 minutes of moderate-intense aerobic physical activity per week. So, in this blog, we will cover the common reasons you are not losing weight despite regular exercise.
This is a great question if you do not see the weight loss results you want despite exercising. Not all exercise is created to cater to weight loss. Some are designed for muscle and bone strengthening, while some may add weight to your body. Some exercise may be good for physical development, while some may improve internal organ functioning.
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So, the most important thing is to find an exercise that suits your body and a routine that you can enjoy and stick to long-term. As consistency is the key to seeing results, several factors affect weight loss results.
Still struggling to lose weight despite exercising? Here are some reasons why your exercise efforts may not be reaping their intended results.
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While it is important to remain consistent during your weight loss journey, it is equally important to avoid the temptation of evaluating the success of your efforts on metrics like overall kg’s lost from start to finish. Remember that your body can sometimes make changes that a scale can't measure, so evaluating your physical fitness on how much weight you lose can be a disservice to your efforts. Make it a point to focus your efforts on intensity as much as frequency and round it out with adequate rest and balanced eating and your body will thank you by letting go of those excess kilos.For many of us, losing weight is welcomed! However, if you are losing weight or you have lost your appetite and there is no real explanation for this, then you should contact your GP practice.
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