How Long To Lose Weight On Metformin Pcos

Find out why metformin helps with weight loss, but more importantly what works better and how to finally lose weight if you have PCOS.

So why is metformin, a medication used to lower blood sugar and treat insulin resistance, used to treat estrogen/progesterone imbalances in women?

In fact, many physicians recommend that ALL women with PCOS should be treated for insulin resistance regardless of what their fasting insulin and fasting blood sugar levels are.

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This means that the root cause of PCOS (at least the majority of it) is insulin resistance, and this is why metformin is so commonly used to treat it.

Insulin resistance causes a block of glucose uptake in your skeletal muscles which results in a lower metabolism (and weight gain), insulin also directly acts on your ovaries and adrenals increasing androgens like testosterone and DHEA.

It’s also the action of insulin on your pituitary that results in increased LH production which over-stimulates your ovaries resulting in the characteristic “cysts” of PCOS.

Weight Loss Vs. Metformin Against Pcos

The truth is that while insulin resistance is the underlying cause of PCOS, there are much better ways to treat this problem and it turns out that metformin is NOT the best medication to reduce blood sugar OR help with weight loss.

Metformin is a biguanide medication that acts through a number of mechanisms, but the most important one is the sensitization of your cells to insulin.

That means that metformin actually makes your body more SENSITIVE to the insulin that is already in circulation – and this is a good thing, we want this to happen.

The Facts About Metformin For Pcos — Pcos Living

Insulin is a hormone that is secreted from your body and it’s designed to help your body store glucose or blood sugar.

Basically what happens is your body pumps out insulin at higher levels than normal and insulin stays around longer than it should in your blood.

So the next time you have a meal, instead of that glucose being used as an energy source for your muscles, brain tissue, heart tissue, etc. it’s instead stuffed right into your fat cells – making you gain weight.

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This is also why low-calorie diets won’t work in the presence of insulin resistance, it doesn’t matter if you eat 1, 000 calories if your insulin levels are high.

Studies have shown (2) that some patients with PCOS taking metformin (at various doses) may lose up to 4% of their body fat over an 8-month period:

Patients on 2500mg of metformin lost about twice as much weight as patients only taking 1, 500mg of metformin over the same period of time.

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This information is helpful because it does indeed prove that treating insulin resistance in patients with PCOS does result in weight loss, and it seems that this weight loss is dose-dependent.

As you can see from the study above the dosages were quite high (up to 2, 500mg per day) and most Doctors start patients on doses as low as 500mg per day and may never increase it from there.

If you consider that your dose matters quite a bit in terms of how much weight patients lose, then you can easily understand that more efficacious medications are likely to result in even more weight loss than metformin.

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And this helps us understand why certain patients with PCOS will tell you that metformin was life-changing for them while other patients insist that metformin is useless for them.

Having said all of this, I still want to make the case for using metformin even if you decide you may need a stronger and better alternative.

So even if metformin doesn’t help you with weight loss it doesn’t mean you should necessarily stop taking it, especially since it may be helping in other ways.

Facts About Metformin And Pcos

The connection between thyroid disease and PCOS is very important because hypothyroidism makes all of the symptoms of PCOS worse and there is an emerging relationship between these two conditions in the literature (7).

There happen to be some very helpful and newer medications that have come out recently that show special promise in treating patients with PCOS.

I can tell you from first-hand experience that these medications are far more powerful than metformin at reducing insulin levels AND helping with weight loss.

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Because they are FDA-approved for type II diabetes many physicians may not be aware of how helpful they can be, which means it’s up to you to look into them and be your own advocate.

Because they work so well and represent an accidental discovery of why exactly so many patients gain weight and have weight loss resistance: the combination of hyperglucagonemia and hyperleptinemia.

Studies have shown that the longer you take this medication the more weight loss you have, up to as much as 20 kgs (40+ pounds).

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It compared a GLP-1 agonist by itself to the combination of metformin plus the GLP-1 agonist which resulted in significant weight loss over either medication alone.

Meaning they took patients who previously took metformin but didn’t lose ANY weight, and they put these patients on the combination of metformin plus GLP-1 agonist and they did, in fact, lose weight.

This is important because patients who don’t lose weight on metformin are considered to be more resistant than others (and therefore more difficult to treat).

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Chances are high that if you are reading this article you are likely also difficult to treat – otherwise, you wouldn’t have a need to look for an alternative!

One of the reasons these medications are so helpful likely has to do with how GLP-1 agonists benefit other hormones in your body.

In order to get the kind of results I am talking about here you have to make sure you are using the right type of GLP-1 agonist and at the right dose.

Metformin For Pcos (benefits And Side Effects)

You can find more information about how I use these medications, how to titrate your dosing and how to adjust dosing for the most benefit in my weight loss and hormone mastery guide.

If you are serious about getting results then you will need to use a combination of supplements, medications (combinations of medications), and dietary changes.

Here we will discuss relevant supplements that can actually dramatically reduce insulin resistance and can safely be used with metformin (or GLP-1 agonists).

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Part of the reason that patients don’t get results is that they don’t use high-quality supplements and they don’t use a high enough dose.

That means taking an active approach and consciously changing your diet to exclude the types of foods that spike insulin and make PCOS worse.

Third: You should eat organic and grass-fed whenever possible (as someone with PCOS you want to avoid any excess artificial growth hormones)

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You will want to start with one diet and then adjust how much, how often, and your macromolecule ratios based on your specific needs.

And that means a combination of taking the right type and dose of medication, changing your diet, and taking the right type and dose of supplements.

Hey! I'm Westin Childs D.O. (former Osteopathic Physician). I don't practice medicine anymore and instead specialize in helping people like YOU who have thyroid problems, hormone imbalances, and weight loss resistance. I love to write and share what I've learned over the years. I also happen to formulate the best supplements on the market (well, at least in my opinion!) and I'm proud to say that over 80, 000+ people have used them over the last 7 years. You can read more about my own personal health journey and why I am so passionate about what I do.

Pcos Belly Fat

Hey There! I'm Dr. Westin Childs. Welcome to my website! This resource is dedicated to helping people with thyroid problems, hormone imbalances, and weight loss problems get the help that they need.

I am a former Doctor of Osteopathic Medicine (no longer practicing) that now focuses on producing the information you see here while also formulating some of the best supplements on the market (in my HUMBLE opinion) :)

This content is strictly the opinion of Dr. Westin Childs and is for educational and information purposes only. I go to great lengths to help my users better understand their health; however, the content you see here is not a substitute for medical advice. If you have questions regarding your health you should seek qualified information from a medical professional or your doctor.Why is Metformin prescribed to so many women with PCOS? You’ll learn the connection between insulin resistance, PCOS symptoms, and Metformin’s impact.

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What about inositols? We dive deep into the research between Metformin and Inositol supplements! Inositols are one of the most researched supplements for PCOS and we want you to know about it!

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While Tallene is a Registered Dietitian and Sirak a Personal Trainer, this podcast provides general information about PCOS. It is not meant to serve as fitness, nutrition or medical advice related to your individual needs. If you have questions, please talk to a medical professional. For our full privacy policy, please click on the following link: (bit.ly/PCOSPrivacyPolicy)

How To Lose Weight With Pcos → Why It's So Hard To Lose Weight With Pcos

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